This page describes pharmacological agents that may have legal restrictions, side effects, and drug interactions in your jurisdiction. Information is for educational research only — consult a clinician before considering any compound.
Surface here is educational only; do not use without medical supervision. Our editorial verdict is SKIP-FOR-NOW — current cost / risk / redundancy puts it below the line.
AICAR
The original "exercise in a pill" — direct AMPK activator that gave sedentary mice +44% endurance in Narkar 2008.
Aliases (4)
Overview
What is AICAR?
The original "exercise in a pill" — direct AMPK activator that gave sedentary mice +44% endurance in Narkar 2008. In humans: near-zero oral bioavailability, injection-only, no FDA-approved form, WADA-banned, and same gray-market supply chain as worst of the AAS world. Metformin / berberine / actual exercise hit the same target with vastly better risk profile.
What to Expect
- Week 1Tolerability and dose-response.
- Week 2-4Early effect window.
- Week 4-8Peak benefit assessment.
- Week 8+Cycle decision point.
How was your experience with this compound?
Anonymous · one vote per session · results below at 5+ votes.
See something off?
Most of this wiki is AI-generated. Suggest a correction, dosing update, or new evidence — we review every submission.