This page describes pharmacological agents that may have legal restrictions, side effects, and drug interactions in your jurisdiction. Information is for educational research only — consult a clinician before considering any compound.

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Bromelain

Pineapple-stem proteolytic enzyme complex (cysteine proteases bromelain + ananain + comosain) with a real but B-tier anti-inflammatory profile — best-evidenced for post-surgical and post-traumatic …

Aliases (1)
BROMELAIN
TYPICAL DOSE
000 mg divided into 2–3 doses
ROUTE
CYCLE
STORAGE

Overview

What is Bromelain?


To prevent hypercholesterolemia for cheaper (and likely m"

-Raw garlic cloves in manuka honey

Irwin Naturals Pure Defense Mushroom-8 Immune

https://a.co/d/c6pIte8

Clean Nutraceuticals NAC Supplement N-Acetyl Cysteine Vitamin D3 K2 Zinc Quercetin Sarracenia Purpurea with Elderberry Holy Basil Bee Propolis Bromelain L-Lysine

https://a.co/d/7G2rRqT

Propolis Throat Spray by Beekeeper's Naturals - 95% Bee Propolis Extract, Natural Immune Support

https://a.co/d/4KBTjNJ"

  • sourceThread: "r/Nootropics" permalink: "https://www.reddit.com/r/Nootropics/comments/rwcajm/nac_helps_anxiety_depression_sleep_apnea_now_covid/hrbbx8r/" score: 10 createdAt: "2022-01-05T04:49:38Z" authorHandle: "5ccaff7b" isOriginalPoster: false isPostBody: false postTitle: null wordCount: 67 excerpt: "I've been doing a fairly regular stack of C, D3, Zinc, Quercetin, Bromelain, NAC, Mg and Melatonin for a few months. I got sick last week for the first time during the pandemic and was at 80% within 24 hours, 100% aside from lingering sniffle within 3 days.

Anecdotal, but definitely seemed to help. I upped the NAC, C and Quercetin doses when I started feeling symptoms."

  • sourceThread: "r/Nootropics" permalink: "https://www.reddit.com/r/Nootropics/comments/vjnbqc/nootropics_ive_tried_for_brain_fog_ranked_long/idmmgb3/" score: 9 createdAt: "2022-06-25T00:07:18Z" authorHandle: "09c33016" isOriginalPoster: false isPostBody: false postTitle: null wordCount: 327 excerpt: "I can't believe the lack of public information on this topic. The medical community has given absolutely zero good actionable advice on this topic, demonstrating once again that mainstream medicine makes no basically no attempt to treat chronic illnesses which can't directly be tested for (unlike, e.g. multiple sclerosis). It's a bit criminal.
  1. Fibrinolytic drugs. Disordered (typically excessive) blood coagulation is a major aspect of long covid. Fibrinolytic drugs dissolve fibrin agglomerations, and commonly other related things like atherosclerotic plaques and amyloid beta deposits. They're amazing supplements, a must-try for long covid. [The cfsremission.com blog is where I learned about this; an incredible resource for all chronic illness sufferers](https://cfsremission.com/tr"

Taking cortisone for a few days before an MRI made me realize how inflammed I was. Euphoric relief washed over my whole body. I had little idea what cortisone even was, had to look it up and find out it's an anti-inflammatory. Prior, I'd have simply reported feelings of fatigue, low mood, irritability, insomnia, that are always easy to accept as just a slump/phase (and could be explained by my real life situation at the time, lots of stress, dissatisfied, night shifts etc). I was able to find that same kind of relief in bromelain."

Onion quercetin is better absorbed than apple quercetin"

I have osteoarthritis and this combo has been helping with the pain."

I've been using it for 3 months with very good results and, usually, kicks in within 15-20 mins.

I had been searching for something to replace OTC anti-histamine drugs as they make me so drowsy and, basically, unproductive for half to a full day (probably removing too much histamine from the brain but idk).

Quercetin (with Bromelain) really works far better than I was expecting. I found L-theanine comes second to it but takes a little longer to kick in and I'm not certain it's as effective but still worth trying.

I've also read in a study (and I've lost the source now) that Cranberry increases Quercetin absorption (along with Bromelain and something fatty). I've tried them all but can't really vouch for increased effec"

I've only been with a few days of fever last month in the last 7 years. However, I forgotten how old I am (and how time flies), it's actually 9.5 years ago I had the flu, strep throat or the cold last.

Base stack (daily):

500mg ascorbyl palmitat (superior form of C-vit) - replaced ascorbic acid after I had developed two lipomas. AP has anti-tumor effects in fatty tissue, which is what lipomas are. One went away by itself, other got removed. None have re-emerged since.

High quality krill oil (1.5g EPA)

30mg zinc (with some cobber)

500mg Magnesium complex

125mcg D3 (with K-complex and iodine)

12mg astaxanthin

B-vit complex (every other day)

Bromelain 300mg / quercetin 1g - added to the stack after a pa"

  • (edit: also Vitamin K2)
  • Tocomin Suprabio (Vitamin E blend, primarily for the d-gamma-tocotrienol to combo with quercetin)
  • Quercetin (combo with tocotrineols for senescent cell clearing)
  • Sulforaphane (broccoli seed extract)
  • Watercress (DNA repair)
  • Tumeric Circumin w/ pepper (anti-inflammatory/anti-oxidant/brain health)
  • Resveratrol 200 mg (anti-cancer/anti-oxidant/caloric restrictor)
  • Pterostilbene (anti-oxidant, anti-cancer, brain health, longevity)
  • Gynostemma (neuroprotective, anti-cancer, anti-oxidant)
  • Bromelain (anti-inflammatory)
  • Alpha Lipoic Acid (adaptogen)
  • Olive Leaf (arterial health, anti-cancer, neuroprotective)
  • Ginko Biloba (brain health)
  • Grapefruit Pectin (artery health)
  • Cod Liver Oil (brain fat)
  • C60oo (immortality)
  • Muira Puama (bra"

Here are two substances with novel mechansims of action (they are not direct vasodilators):

Fibrinolytic drugs. Bromelain or, even better, nattokinase. These substances can improve cerebral microcirculation, especially if you have any chronic inflammation. (If you don't have chronic inflammation, it's sort of unlikely that you need more blood in your brain anyway; too much blood in your brain is not good).

Intranasal insulin also increases cerebral blood flow.

Both of these are some of my absolute favorites."

sometimes a synergistic cocktail might be something to try. It's going to be a long list (of mostly plant alkaloids); here's a small fraction of some because my memory is bad

rutin, bromelaine, berberine ( tiny.cc/2ghghz ), tumeric/ginger (dose carefully), olive leaf

prescription of cannabis?

exercise

avoid selenium deficiency but dose carefully and along with vit e . also avoid less common deficiencies.

and mostly try to get at the root of the cause. you might try switching to all organic especially for grains. there is a glyphosate gout epidemic ongoing; long term abuse of this bioaccumulation often leads to allergies to mis"

Let's talk about eating medicinal food that is inexpensive and quick to prepare.

I would like to share with you that sardines are $1/can at the grocery store right now. They are high in vitamin B12, vitamin D, and healthy fish fats. I am thinking of how to share the recipe of Mediterranean Sardines (smashed with a fork) and mayonnaise with whole-wheat saltine crackers to everyone, which is the definition of a social activity that looks out for everyone. Sardines are essential to understand as a fatty fish for $1/serving. They will raise vitamin D levels this winter. If you are like me, you will feel calm, rejuvenated, and awake from the mega-dose of B12 alone.

A distant second meal is baked potato with b"

Alpha Brain is kinda expensive and the most useful ingredient is probably just bacopa, which can be sourced elsewhere for much less. e.g. swanson bacognize or vitacost bacognize.

ALCAR is unlikely to be very remarkable for focus and recall in healthy people. Benefits are usually remarked in the context of disease such as chronic fatigue and later life decline: http://examine.com/supplements/l-carnitine/ - Harmless enough to trial it yourself though.

Other anti-inflammatory things: Pycnogenol (probably extends to the cheaper pine park), Spirulina, [Cissus](http:"

  1. Trace Mineral Drops—Makes any and all water mineral.

  2. L-Theanine- Focus and calm

  3. Cod lover oil. Bio available and rancid proof forms of epa and dha, plus nice ratios of vitamin a and d

  4. L-Tyrosine. Replenishes dopamine

  5. Bromelain Extract- my current girl I’m dating and every I’ve dated since taking this loves swallowing."

I've accidentally been in close proximity or even hugged people that was later hit with covid 5 times that I know of. Most of these have probably been omicron from the last month.

No positive tests yet. I did have flu-like symptoms with slight fever a few days in December though. Was 100% in 3 days.

Before that I hadn't been sick one day in about 7 years. I highly, highly recommend this stack for anyone. Covid or not."

  • sourceThread: "r/Nootropics" permalink: "https://www.reddit.com/r/Nootropics/comments/c5wzfp/nootropics_fueled_successlife_change/es6ml2q/" score: 4 createdAt: "2019-06-27T16:24:47Z" authorHandle: "633bef63" isOriginalPoster: false isPostBody: false postTitle: null wordCount: 108 excerpt: "I suffer from depression, anxiety, and OCD. I still take some pharmaceuticals but have been able to drastically lower my doses (I used to be basically a zombie) thanks to intermittent use of phenibut, taurine, and inositol. Those three have helped me succeed at my job whereas before I was really struggling due to the high doses of pharmaceuticals. I also take enzymes with bromelain in them multiple times a day to help with wound healing (the OCD causes me to pick at my own skin), and NAC when I remember.

EDIT: I also take kratom with black coffee a few times a day. That helps with energy." attribution: sources: - name: "dopamine.club" role: "community aggregate stats, dose distribution, stack synergies, AI-seeded interactions" url: "https://dopamine.club/substances/bromelain/" - name: "reddit" role: "paragraph-level community anecdotes" url: "https://reddit.com" text: "Aggregated from creator-curated and community sources. Verify dose, sourcing, and safety before use."

=== community-data-block:end ===



To prevent hypercholesterolemia for cheaper (and likely m"

-Raw garlic cloves in manuka honey

Irwin Naturals Pure Defense Mushroom-8 Immune

https://a.co/d/c6pIte8

Clean Nutraceuticals NAC Supplement N-Acetyl Cysteine Vitamin D3 K2 Zinc Quercetin Sarracenia Purpurea with Elderberry Holy Basil Bee Propolis Bromelain L-Lysine

https://a.co/d/7G2rRqT

Propolis Throat Spray by Beekeeper's Naturals - 95% Bee Propolis Extract, Natural Immune Support

https://a.co/d/4KBTjNJ"

  • sourceThread: "r/Nootropics" permalink: "https://www.reddit.com/r/Nootropics/comments/rwcajm/nac_helps_anxiety_depression_sleep_apnea_now_covid/hrbbx8r/" score: 10 createdAt: "2022-01-05T04:49:38Z" authorHandle: "5ccaff7b" isOriginalPoster: false isPostBody: false postTitle: null wordCount: 67 excerpt: "I've been doing a fairly regular stack of C, D3, Zinc, Quercetin, Bromelain, NAC, Mg and Melatonin for a few months. I got sick last week for the first time during the pandemic and was at 80% within 24 hours, 100% aside from lingering sniffle within 3 days.

Anecdotal, but definitely seemed to help. I upped the NAC, C and Quercetin doses when I started feeling symptoms."

  • sourceThread: "r/Nootropics" permalink: "https://www.reddit.com/r/Nootropics/comments/vjnbqc/nootropics_ive_tried_for_brain_fog_ranked_long/idmmgb3/" score: 9 createdAt: "2022-06-25T00:07:18Z" authorHandle: "09c33016" isOriginalPoster: false isPostBody: false postTitle: null wordCount: 327 excerpt: "I can't believe the lack of public information on this topic. The medical community has given absolutely zero good actionable advice on this topic, demonstrating once again that mainstream medicine makes no basically no attempt to treat chronic illnesses which can't directly be tested for (unlike, e.g. multiple sclerosis). It's a bit criminal.
  1. Fibrinolytic drugs. Disordered (typically excessive) blood coagulation is a major aspect of long covid. Fibrinolytic drugs dissolve fibrin agglomerations, and commonly other related things like atherosclerotic plaques and amyloid beta deposits. They're amazing supplements, a must-try for long covid. [The cfsremission.com blog is where I learned about this; an incredible resource for all chronic illness sufferers](https://cfsremission.com/tr"

Taking cortisone for a few days before an MRI made me realize how inflammed I was. Euphoric relief washed over my whole body. I had little idea what cortisone even was, had to look it up and find out it's an anti-inflammatory. Prior, I'd have simply reported feelings of fatigue, low mood, irritability, insomnia, that are always easy to accept as just a slump/phase (and could be explained by my real life situation at the time, lots of stress, dissatisfied, night shifts etc). I was able to find that same kind of relief in bromelain."

Onion quercetin is better absorbed than apple quercetin"

I have osteoarthritis and this combo has been helping with the pain."

I've been using it for 3 months with very good results and, usually, kicks in within 15-20 mins.

I had been searching for something to replace OTC anti-histamine drugs as they make me so drowsy and, basically, unproductive for half to a full day (probably removing too much histamine from the brain but idk).

Quercetin (with Bromelain) really works far better than I was expecting. I found L-theanine comes second to it but takes a little longer to kick in and I'm not certain it's as effective but still worth trying.

I've also read in a study (and I've lost the source now) that Cranberry increases Quercetin absorption (along with Bromelain and something fatty). I've tried them all but can't really vouch for increased effec"

I've only been with a few days of fever last month in the last 7 years. However, I forgotten how old I am (and how time flies), it's actually 9.5 years ago I had the flu, strep throat or the cold last.

Base stack (daily):

500mg ascorbyl palmitat (superior form of C-vit) - replaced ascorbic acid after I had developed two lipomas. AP has anti-tumor effects in fatty tissue, which is what lipomas are. One went away by itself, other got removed. None have re-emerged since.

High quality krill oil (1.5g EPA)

30mg zinc (with some cobber)

500mg Magnesium complex

125mcg D3 (with K-complex and iodine)

12mg astaxanthin

B-vit complex (every other day)

Bromelain 300mg / quercetin 1g - added to the stack after a pa"

  • (edit: also Vitamin K2)
  • Tocomin Suprabio (Vitamin E blend, primarily for the d-gamma-tocotrienol to combo with quercetin)
  • Quercetin (combo with tocotrineols for senescent cell clearing)
  • Sulforaphane (broccoli seed extract)
  • Watercress (DNA repair)
  • Tumeric Circumin w/ pepper (anti-inflammatory/anti-oxidant/brain health)
  • Resveratrol 200 mg (anti-cancer/anti-oxidant/caloric restrictor)
  • Pterostilbene (anti-oxidant, anti-cancer, brain health, longevity)
  • Gynostemma (neuroprotective, anti-cancer, anti-oxidant)
  • Bromelain (anti-inflammatory)
  • Alpha Lipoic Acid (adaptogen)
  • Olive Leaf (arterial health, anti-cancer, neuroprotective)
  • Ginko Biloba (brain health)
  • Grapefruit Pectin (artery health)
  • Cod Liver Oil (brain fat)
  • C60oo (immortality)
  • Muira Puama (bra"

Here are two substances with novel mechansims of action (they are not direct vasodilators):

Fibrinolytic drugs. Bromelain or, even better, nattokinase. These substances can improve cerebral microcirculation, especially if you have any chronic inflammation. (If you don't have chronic inflammation, it's sort of unlikely that you need more blood in your brain anyway; too much blood in your brain is not good).

Intranasal insulin also increases cerebral blood flow.

Both of these are some of my absolute favorites."

sometimes a synergistic cocktail might be something to try. It's going to be a long list (of mostly plant alkaloids); here's a small fraction of some because my memory is bad

rutin, bromelaine, berberine ( tiny.cc/2ghghz ), tumeric/ginger (dose carefully), olive leaf

prescription of cannabis?

exercise

avoid selenium deficiency but dose carefully and along with vit e . also avoid less common deficiencies.

and mostly try to get at the root of the cause. you might try switching to all organic especially for grains. there is a glyphosate gout epidemic ongoing; long term abuse of this bioaccumulation often leads to allergies to mis"

Let's talk about eating medicinal food that is inexpensive and quick to prepare.

I would like to share with you that sardines are $1/can at the grocery store right now. They are high in vitamin B12, vitamin D, and healthy fish fats. I am thinking of how to share the recipe of Mediterranean Sardines (smashed with a fork) and mayonnaise with whole-wheat saltine crackers to everyone, which is the definition of a social activity that looks out for everyone. Sardines are essential to understand as a fatty fish for $1/serving. They will raise vitamin D levels this winter. If you are like me, you will feel calm, rejuvenated, and awake from the mega-dose of B12 alone.

A distant second meal is baked potato with b"

Alpha Brain is kinda expensive and the most useful ingredient is probably just bacopa, which can be sourced elsewhere for much less. e.g. swanson bacognize or vitacost bacognize.

ALCAR is unlikely to be very remarkable for focus and recall in healthy people. Benefits are usually remarked in the context of disease such as chronic fatigue and later life decline: http://examine.com/supplements/l-carnitine/ - Harmless enough to trial it yourself though.

Other anti-inflammatory things: Pycnogenol (probably extends to the cheaper pine park), Spirulina, [Cissus](http:"

  1. Trace Mineral Drops—Makes any and all water mineral.

  2. L-Theanine- Focus and calm

  3. Cod lover oil. Bio available and rancid proof forms of epa and dha, plus nice ratios of vitamin a and d

  4. L-Tyrosine. Replenishes dopamine

  5. Bromelain Extract- my current girl I’m dating and every I’ve dated since taking this loves swallowing."

I've accidentally been in close proximity or even hugged people that was later hit with covid 5 times that I know of. Most of these have probably been omicron from the last month.

No positive tests yet. I did have flu-like symptoms with slight fever a few days in December though. Was 100% in 3 days.

Before that I hadn't been sick one day in about 7 years. I highly, highly recommend this stack for anyone. Covid or not."

  • sourceThread: "r/Nootropics" permalink: "https://www.reddit.com/r/Nootropics/comments/c5wzfp/nootropics_fueled_successlife_change/es6ml2q/" score: 4 createdAt: "2019-06-27T16:24:47Z" authorHandle: "633bef63" isOriginalPoster: false isPostBody: false postTitle: null wordCount: 108 excerpt: "I suffer from depression, anxiety, and OCD. I still take some pharmaceuticals but have been able to drastically lower my doses (I used to be basically a zombie) thanks to intermittent use of phenibut, taurine, and inositol. Those three have helped me succeed at my job whereas before I was really struggling due to the high doses of pharmaceuticals. I also take enzymes with bromelain in them multiple times a day to help with wound healing (the OCD causes me to pick at my own skin), and NAC when I remember.

EDIT: I also take kratom with black coffee a few times a day. That helps with energy." attribution: sources: - name: "dopamine.club" role: "community aggregate stats, dose distribution, stack synergies, AI-seeded interactions" url: "https://dopamine.club/substances/bromelain/" - name: "reddit" role: "paragraph-level community anecdotes" url: "https://reddit.com" text: "Aggregated from creator-curated and community sources. Verify dose, sourcing, and safety before use."

=== community-data-block:end ===



To prevent hypercholesterolemia for cheaper (and likely m"

-Raw garlic cloves in manuka honey

Irwin Naturals Pure Defense Mushroom-8 Immune

https://a.co/d/c6pIte8

Clean Nutraceuticals NAC Supplement N-Acetyl Cysteine Vitamin D3 K2 Zinc Quercetin Sarracenia Purpurea with Elderberry Holy Basil Bee Propolis Bromelain L-Lysine

https://a.co/d/7G2rRqT

Propolis Throat Spray by Beekeeper's Naturals - 95% Bee Propolis Extract, Natural Immune Support

https://a.co/d/4KBTjNJ"

  • sourceThread: "r/Nootropics" permalink: "https://www.reddit.com/r/Nootropics/comments/rwcajm/nac_helps_anxiety_depression_sleep_apnea_now_covid/hrbbx8r/" score: 10 createdAt: "2022-01-05T04:49:38Z" authorHandle: "5ccaff7b" isOriginalPoster: false isPostBody: false postTitle: null wordCount: 67 excerpt: "I've been doing a fairly regular stack of C, D3, Zinc, Quercetin, Bromelain, NAC, Mg and Melatonin for a few months. I got sick last week for the first time during the pandemic and was at 80% within 24 hours, 100% aside from lingering sniffle within 3 days.

Anecdotal, but definitely seemed to help. I upped the NAC, C and Quercetin doses when I started feeling symptoms."

  • sourceThread: "r/Nootropics" permalink: "https://www.reddit.com/r/Nootropics/comments/vjnbqc/nootropics_ive_tried_for_brain_fog_ranked_long/idmmgb3/" score: 9 createdAt: "2022-06-25T00:07:18Z" authorHandle: "09c33016" isOriginalPoster: false isPostBody: false postTitle: null wordCount: 327 excerpt: "I can't believe the lack of public information on this topic. The medical community has given absolutely zero good actionable advice on this topic, demonstrating once again that mainstream medicine makes no basically no attempt to treat chronic illnesses which can't directly be tested for (unlike, e.g. multiple sclerosis). It's a bit criminal.
  1. Fibrinolytic drugs. Disordered (typically excessive) blood coagulation is a major aspect of long covid. Fibrinolytic drugs dissolve fibrin agglomerations, and commonly other related things like atherosclerotic plaques and amyloid beta deposits. They're amazing supplements, a must-try for long covid. [The cfsremission.com blog is where I learned about this; an incredible resource for all chronic illness sufferers](https://cfsremission.com/tr"

Taking cortisone for a few days before an MRI made me realize how inflammed I was. Euphoric relief washed over my whole body. I had little idea what cortisone even was, had to look it up and find out it's an anti-inflammatory. Prior, I'd have simply reported feelings of fatigue, low mood, irritability, insomnia, that are always easy to accept as just a slump/phase (and could be explained by my real life situation at the time, lots of stress, dissatisfied, night shifts etc). I was able to find that same kind of relief in bromelain."

Onion quercetin is better absorbed than apple quercetin"

I have osteoarthritis and this combo has been helping with the pain."

I've been using it for 3 months with very good results and, usually, kicks in within 15-20 mins.

I had been searching for something to replace OTC anti-histamine drugs as they make me so drowsy and, basically, unproductive for half to a full day (probably removing too much histamine from the brain but idk).

Quercetin (with Bromelain) really works far better than I was expecting. I found L-theanine comes second to it but takes a little longer to kick in and I'm not certain it's as effective but still worth trying.

I've also read in a study (and I've lost the source now) that Cranberry increases Quercetin absorption (along with Bromelain and something fatty). I've tried them all but can't really vouch for increased effec"

I've only been with a few days of fever last month in the last 7 years. However, I forgotten how old I am (and how time flies), it's actually 9.5 years ago I had the flu, strep throat or the cold last.

Base stack (daily):

500mg ascorbyl palmitat (superior form of C-vit) - replaced ascorbic acid after I had developed two lipomas. AP has anti-tumor effects in fatty tissue, which is what lipomas are. One went away by itself, other got removed. None have re-emerged since.

High quality krill oil (1.5g EPA)

30mg zinc (with some cobber)

500mg Magnesium complex

125mcg D3 (with K-complex and iodine)

12mg astaxanthin

B-vit complex (every other day)

Bromelain 300mg / quercetin 1g - added to the stack after a pa"

  • (edit: also Vitamin K2)
  • Tocomin Suprabio (Vitamin E blend, primarily for the d-gamma-tocotrienol to combo with quercetin)
  • Quercetin (combo with tocotrineols for senescent cell clearing)
  • Sulforaphane (broccoli seed extract)
  • Watercress (DNA repair)
  • Tumeric Circumin w/ pepper (anti-inflammatory/anti-oxidant/brain health)
  • Resveratrol 200 mg (anti-cancer/anti-oxidant/caloric restrictor)
  • Pterostilbene (anti-oxidant, anti-cancer, brain health, longevity)
  • Gynostemma (neuroprotective, anti-cancer, anti-oxidant)
  • Bromelain (anti-inflammatory)
  • Alpha Lipoic Acid (adaptogen)
  • Olive Leaf (arterial health, anti-cancer, neuroprotective)
  • Ginko Biloba (brain health)
  • Grapefruit Pectin (artery health)
  • Cod Liver Oil (brain fat)
  • C60oo (immortality)
  • Muira Puama (bra"

Here are two substances with novel mechansims of action (they are not direct vasodilators):

Fibrinolytic drugs. Bromelain or, even better, nattokinase. These substances can improve cerebral microcirculation, especially if you have any chronic inflammation. (If you don't have chronic inflammation, it's sort of unlikely that you need more blood in your brain anyway; too much blood in your brain is not good).

Intranasal insulin also increases cerebral blood flow.

Both of these are some of my absolute favorites."

sometimes a synergistic cocktail might be something to try. It's going to be a long list (of mostly plant alkaloids); here's a small fraction of some because my memory is bad

rutin, bromelaine, berberine ( tiny.cc/2ghghz ), tumeric/ginger (dose carefully), olive leaf

prescription of cannabis?

exercise

avoid selenium deficiency but dose carefully and along with vit e . also avoid less common deficiencies.

and mostly try to get at the root of the cause. you might try switching to all organic especially for grains. there is a glyphosate gout epidemic ongoing; long term abuse of this bioaccumulation often leads to allergies to mis"

Let's talk about eating medicinal food that is inexpensive and quick to prepare.

I would like to share with you that sardines are $1/can at the grocery store right now. They are high in vitamin B12, vitamin D, and healthy fish fats. I am thinking of how to share the recipe of Mediterranean Sardines (smashed with a fork) and mayonnaise with whole-wheat saltine crackers to everyone, which is the definition of a social activity that looks out for everyone. Sardines are essential to understand as a fatty fish for $1/serving. They will raise vitamin D levels this winter. If you are like me, you will feel calm, rejuvenated, and awake from the mega-dose of B12 alone.

A distant second meal is baked potato with b"

Alpha Brain is kinda expensive and the most useful ingredient is probably just bacopa, which can be sourced elsewhere for much less. e.g. swanson bacognize or vitacost bacognize.

ALCAR is unlikely to be very remarkable for focus and recall in healthy people. Benefits are usually remarked in the context of disease such as chronic fatigue and later life decline: http://examine.com/supplements/l-carnitine/ - Harmless enough to trial it yourself though.

Other anti-inflammatory things: Pycnogenol (probably extends to the cheaper pine park), Spirulina, [Cissus](http:"

  1. Trace Mineral Drops—Makes any and all water mineral.

  2. L-Theanine- Focus and calm

  3. Cod lover oil. Bio available and rancid proof forms of epa and dha, plus nice ratios of vitamin a and d

  4. L-Tyrosine. Replenishes dopamine

  5. Bromelain Extract- my current girl I’m dating and every I’ve dated since taking this loves swallowing."

I've accidentally been in close proximity or even hugged people that was later hit with covid 5 times that I know of. Most of these have probably been omicron from the last month.

No positive tests yet. I did have flu-like symptoms with slight fever a few days in December though. Was 100% in 3 days.

Before that I hadn't been sick one day in about 7 years. I highly, highly recommend this stack for anyone. Covid or not."

  • sourceThread: "r/Nootropics" permalink: "https://www.reddit.com/r/Nootropics/comments/c5wzfp/nootropics_fueled_successlife_change/es6ml2q/" score: 4 createdAt: "2019-06-27T16:24:47Z" authorHandle: "633bef63" isOriginalPoster: false isPostBody: false postTitle: null wordCount: 108 excerpt: "I suffer from depression, anxiety, and OCD. I still take some pharmaceuticals but have been able to drastically lower my doses (I used to be basically a zombie) thanks to intermittent use of phenibut, taurine, and inositol. Those three have helped me succeed at my job whereas before I was really struggling due to the high doses of pharmaceuticals. I also take enzymes with bromelain in them multiple times a day to help with wound healing (the OCD causes me to pick at my own skin), and NAC when I remember.

EDIT: I also take kratom with black coffee a few times a day. That helps with energy." attribution: sources: - name: "dopamine.club" role: "community aggregate stats, dose distribution, stack synergies, AI-seeded interactions" url: "https://dopamine.club/substances/bromelain/" - name: "reddit" role: "paragraph-level community anecdotes" url: "https://reddit.com" text: "Aggregated from creator-curated and community sources. Verify dose, sourcing, and safety before use."

=== community-data-block:end ===


Peptide Interactions

Bromelain + quercetin (the classic stack).
Synergistic

Most-combined-with at 85 community mentions. Mechanism: (a) mutual absorption enhancement — community data and mechanistic studies suggest bromelain improves…

Bromelain + curcumin (Meriva or other phytosome).
Synergistic

Independent anti-inflammatory mechanisms (curcumin: NF-κB + COX-2 + JAK/STAT; bromelain: bradykinin + cytokine + fibrin). Effects appear additive in post-sur…

Bromelain + omega-3 (EPA/DHA).
Synergistic

Omega-3 provides chronic-baseline anti-inflammatory + resolvin-mediated resolution; bromelain provides acute-event proteolytic action. Mechanistically comple…

Bromelain + boswellia (5-LOX inhibitor).
Synergistic

Multi-pathway anti-inflammatory stack popular in OA. Mechanistically additive (boswellia hits 5-LOX → leukotrienes; bromelain hits NF-κB + bradykinin).

Bromelain + trypsin + rutoside (Wobenzym / Phlogenzym formulation).
Synergistic

The systemic-enzyme therapy combination — EU-popular, with supportive evidence in OA, TMJ-OA, and post-surgical edema (Bhandari 2024 systematic review).

Anticoagulants:
Avoid

warfarin, DOACs (apixaban, rivaroxaban, dabigatran, edoxaban), heparin, fondaparinux — additive bleeding risk. Theoretical, not always observed clinically, b…

Antiplatelet drugs:
Avoid

aspirin (low-dose cardioprotective or higher), clopidogrel, ticagrelor, prasugrel — additive bleeding risk.

High-dose NSAIDs (ibuprofen, naproxen, diclofenac):
Avoid

additive GI + bleeding risk. Low-dose / occasional NSAID use overlaps acceptably for most users, but chronic high-dose NSAID + bromelain is unwise.

Other fibrinolytic / antiplatelet supplements at high dose:
Avoid

nattokinase, serrapeptase, high-dose fish oil (>3 g/day with anticoagulant), high-dose vitamin E (>800 IU/day), garlic extract — additive bleeding tendency.

Pre/post-surgery window
Avoid

(2 weeks each side): discontinue.

What to Expect

  • Week 1
    Tolerability and dose-response.
  • Week 2-4
    Early effect window.
  • Week 4-8
    Peak benefit assessment.
  • Week 8+
    Cycle decision point.

Side Effects & Safety

  • Common (>5% of users):
    • Mild GI upset (loose stool, mild nausea) — usually transient
    • Mild fatigue (community reports — possibly placebo or coincident)
  • Less common (1–5%):
    • Mild menstrual changes (theoretical mechanism: anticoagulant + uterotonic activity)
    • Headache, mild dizziness
    • Mild palpitations (rare)
  • Rare-serious (<1% but mechanistically real):
    • Pineapple / latex / birch-pollen allergic reaction. Cross-reactivity is well-documented. Anyone with pineapple allergy or latex-fruit syndrome should not take bromelain. Presentation: orofacial swelling, urticaria, occasional bronchospasm. Anaphylaxis is rare but reported.
    • Bleeding-tendency amplification. In-vitro thromboelastography shows PT/aPTT prolongation and platelet aggregation inhibition (PMID 25517253). Clinical translation is small in healthy users but real in users on anticoagulants. Note: one perioperative study (PMID 21611915) found no enhanced bleeding with concomitant LMWH; the signal varies by clinical setting and concomitant drugs.
    • Transaminase elevations — rare, case-reported with very-high-dose chronic use (>3 g/day for months). Reverses on discontinuation.
  • Specific watch periods:
    • First 30–90 minutes of first dose: Allergic reaction is overwhelmingly first-or-second-dose phenomenon. Stop immediately if any orofacial swelling, hives, or shortness of breath.
    • Day 3–7 of a daily course: GI side effects, if they appear, usually emerge here. Reducing per-dose or shifting to BID instead of TID typically resolves.
    • 2 weeks pre-elective surgery: Discontinue. This is the formal recommendation across surgical specialties, despite weak direct clinical evidence of bleeding harm — the precautionary principle applies.

Pregnancy / breastfeeding: Avoid. Theoretical concerns include uterine activity + mild anticoagulation. Clinical data are sparse, and the precautionary stance is universal across regulatory sources.

Pediatric use: Used in clinical trials (Braun 2005 in children with sinusitis — well tolerated at age-adjusted doses); NexoBrid pediatric approval Aug 2024. For non-prescribed supplemental use in <16-year-olds, defer to clinician.

References

Leelakanok N et al. Efficacy and safety of bromelain: A systematic review and meta-analysis. Nutr Health 2023;29(3):479-503 (PMID 37157782)

pubmed.ncbi.nlm.nih.gov · 2023

primary 2023 meta-analysis, 39 RCTs

View Study

Brien S et al. Bromelain as a treatment for osteoarthritis: a review of clinical studies. Evid Based Complement Alternat Med 2004 (PMID 15841258)

pubmed.ncbi.nlm.nih.gov · 2004

foundational OA review

View Study

Hossain MS et al. Bromelain as a natural anti-inflammatory drug: a systematic review. Naunyn Schmiedebergs Arch Pharmacol 2024 (PMID 38676413)

pubmed.ncbi.nlm.nih.gov · 2024

recent mechanism-focused systematic review

View Study

Bhandari R et al. Anti-inflammatory Role of Trypsin, Rutoside, and Bromelain Combination in TMJ Osteoarthritis: A Systematic Review. Cureus 2024 (PMID 38322061)

pubmed.ncbi.nlm.nih.gov · 2024

systemic enzyme combination evidence

View Study

Loo WTY et al. Bromelain-based enzymatic burn debridement: A systematic review. Int Wound J 2024 (PMID 37455553)

pubmed.ncbi.nlm.nih.gov · 2024

NexoBrid post-approval systematic review

View Study
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