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This page describes pharmacological agents that may have legal restrictions, side effects, and drug interactions in your jurisdiction. Information is for educational research only — consult a clinician before considering any compound.

High-risk compound

Surface here is educational only; do not use without medical supervision. Our editorial verdict is SKIP-PERMANENT — risk:benefit fails for the canonical archetype.

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Erythropoietin

Recombinant erythropoietin for medical anemia.

Aliases (9)
EPO · Epogen · Procrit · Aranesp · darbepoetin · epoetin alfa · epoetin beta · rhEPO · human recombinant erythropoietin
TYPICAL DOSE
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ROUTE
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CYCLE
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STORAGE
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Overview

What is Erythropoietin?

Recombinant erythropoietin for medical anemia. Famous endurance-doping agent of the 1990s-2000s. Real performance benefit, real permanent-harm potential (thrombosis at high hematocrit), strict WADA ban with biological passport detection. SKIP-PERMANENT for any tested athlete.

What to Expect

  • Week 1
    Tolerability and dose-response.
  • Week 2-4
    Early effect window.
  • Week 4-8
    Peak benefit assessment.
  • Week 8+
    Cycle decision point.
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Cross-referenced from Erythropoietin
CERA
SKIP-PERMANENT
Pegylated long-acting erythropoietin receptor agonist (third-generation ESA). Roche product. Half-life ~130h vs ~24h for EPO and ~70h for darbepoetin.
HIGH
Roxadustat
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HIF prolyl hydroxylase inhibitor (HIF-PHI) — first-in-class oral small-molecule, isoquinoline-glycinamide scaffold (C19H16N2O5, MW 352.34, CAS 808118-40-3)
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HGH (Human Growth Hormone)
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"191-amino-acid recombinant human growth hormone — direct exogenous replacement of pituitary-secreted GH; full agonist at the GH receptor (GHR). Distinct from every other GH-axis compound on this wiki: GHRH analogs (sermorelin, tesamorelin, CJC-1295) and GH secretagogues (ipamorelin, MK-677, GHRP-2/6) all act upstream at the pituitary to release endogenous GH; HGH is the GH itself, bypassing the entire hypothalamic-pituitary feedback loop."
HIGH
Testosterone Enanthate
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Endogenous androgen / anabolic-androgenic steroid (bioidentical testosterone with enanthate ester)
MEDIUM-HIGH
IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor 1)
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Modified IGF-1 analog — 83-amino-acid recombinant peptide with N-terminal 13-residue extension + Arg-3 substitution. Long-acting, IGFBP-evading IGF-1 receptor agonist; downstream effector of GH axis. Originally developed as a mammalian cell-culture growth supplement, never intended for human therapeutic use.
HIGH