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Polygala tenuifolia
Chinese herb with replicated preclinical BDNF/NGF upregulation and mild AChE inhibition.
Aliases (6)
Overview
What is Polygala tenuifolia?
Chinese herb with replicated preclinical BDNF/NGF upregulation and mild AChE inhibition. Human evidence thin. Some users report vivid dreams + recall boost; others get GI distress. Lower-priority than huperzine A or bacopa as first nootropic.
What to Expect
- Week 1Tolerability and dose-response.
- Week 2-4Early effect window.
- Week 4-8Peak benefit assessment.
- Week 8+Cycle decision point.
Side Effects & Safety
- GI distress (nausea, loose stool) is the most common complaint.
- Headache and anxiety reported at higher doses.
- Theoretical MAO-A interaction — not documented in humans at supplemental doses but worth noting if stacking with serotonergic drugs.
How was your experience with this compound?
Anonymous · one vote per session · results below at 5+ votes.
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