This page describes pharmacological agents that may have legal restrictions, side effects, and drug interactions in your jurisdiction. Information is for educational research only — consult a clinician before considering any compound.
Ibogaine
Surface here is educational only; do not use without medical supervision. Our editorial verdict is SKIP-PERMANENT — risk:benefit fails for the canonical archetype.
Our depth — beyond the mirror
Deeper analysis, verdict reasoning, and per-archetype recommendations from our research team.
▸ Editor's verdict SKIP-PERMANENT HIGH
The most cardiotoxic psychedelic in clinical use. ~1 in 300-400 ibogaine sessions in field clinics ends in death, dominantly via QTc prolongation → torsades → sudden cardiac death. Pre-screening (EKG, electrolytes, no CYP2D6-inducing meds, no other QT-prolonging drugs) reduces but does not eliminate the risk. The legitimate clinical case is opioid use disorder with full medical monitoring — there is real published signal there (Mash 2018, Brown 2018, Davis 2017). For a 20yo with no OUD indication, this is gambling permanent cardiac harm against a recreational psychedelic experience. SKIP-PERMANENT means: not used in this archetype. Even the experimental 18-MC (designed to retain anti-addictive effect without hERG block) is still in early human trials and not available. Flips to OPTIONAL only inside a licensed-clinic + cardiology-cleared + OUD-indication context.
▸ Sourcing deep dive
Schedule I in US; foreign clinics (Mexico, Costa Rica, Brazil) are the legal route. Quality of underground supply varies; potency varies enormously between Tabernanthe iboga root bark batches. 18-MC (non-cardiotoxic analog) in early clinical development at MindMed and others.
▸ Verdict change log
- 2026-06-05 — Initial verdict SKIP-PERMANENT. Cardiac risk too high outside OUD-indication clinical context. (stub)
▸ Open questions / gaps Open
- Whether 18-MC clears Phase 2 with the anti-addictive effect preserved without the cardiac signal.
- Whether magnesium-protected clinical protocols (Cherian 2024) become the standard and reduce field fatality rate.
How was your experience with this compound?
Anonymous · one vote per session · results below at 5+ votes.
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