This page describes pharmacological agents that may have legal restrictions, side effects, and drug interactions in your jurisdiction. Information is for educational research only — consult a clinician before considering any compound.

High-risk compound

Surface here is educational only; do not use without medical supervision. Our editorial verdict is SKIP-PERMANENT — risk:benefit fails for the canonical archetype.

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Ibogaine

Long-acting iboga alkaloid with real published signal for interrupting opioid withdrawal and reducing relapse — used in foreign-clinic OUD treatment industry.

Aliases (5)
Iboga · Tabernanthe iboga · noribogaine · 18-MC · TBG
TYPICAL DOSE
10-20 mg/kg single oral dose, with EKG monitori…
ROUTE
CYCLE
STORAGE

Overview

What is Ibogaine?

Long-acting iboga alkaloid with real published signal for interrupting opioid withdrawal and reducing relapse — used in foreign-clinic OUD treatment industry. Also the most cardiotoxic psychedelic, with ~1/300-400 field-clinic fatality rate from QTc prolongation. SKIP-PERMANENT outside a full medical/cardiology-cleared OUD context.

What to Expect

  • Week 1
    Tolerability and dose-response.
  • Week 2-4
    Early effect window.
  • Week 4-8
    Peak benefit assessment.
  • Week 8+
    Cycle decision point.

Side Effects & Safety

  • Acute experience: ~24-36h waking-dream / "movie-like" autobiographical visions; ataxia; nausea; bradycardia; deep introspective phase.
  • Cardiac: QTc prolongation peaks 6-24h post-dose; torsades risk window extends to 72h. Magnesium loading reduces but does not eliminate.
  • Post-acute: afterglow + insomnia 2-7 days; protracted re-integration.
  • Cerebellar: rare ataxia at supratherapeutic dose; reversibility uncertain.
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