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Rhodiola Rosea 3:1
See parent — Rhodiola rosea
Aliases (3)
Overview
What is Rhodiola Rosea 3:1?
Rhodiola Rosea 3:1 is a standardized concentrated extract of Rhodiola rosea root, where 3 parts raw root yield 1 part finished extract, typically standardized to 3% rosavins and 1% salidroside (the SHR-5 ratio used in clinical trials).
Key Benefits
Standardized form of rhodiola providing reproducible adaptogen effects: reduced stress-related fatigue, improved cognitive performance under sustained mental work, and mood support. Most clinical evidence in fatigue, mild depression, and burnout uses this standardization.
Mechanism of Action
Rosavins and salidroside modulate the HPA axis (blunting cortisol stress response), inhibit MAO-A/MAO-B, and modulate serotonin, dopamine, and norepinephrine signaling. Activate cellular Nrf2/AMPK antioxidant pathways and enhance mitochondrial ATP production.
What to Expect
- Week 1Tolerability and dose-response.
- Week 2-4Early effect window.
- Week 4-8Peak benefit assessment.
- Week 8+Cycle decision point.
References
Panossian et al. 2010 — Rhodiola rosea standardization review (Phytomedicine)
Booker et al. 2016 — quality variability across rhodiola products (J Ethnopharmacol)
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