This page describes pharmacological agents that may have legal restrictions, side effects, and drug interactions in your jurisdiction. Information is for educational research only — consult a clinician before considering any compound.

High-risk compound

Surface here is educational only; do not use without medical supervision. Our editorial verdict is SKIP-PERMANENT — risk:benefit fails for the canonical archetype.

7-OH-Mitragynine

Kratom's high-affinity opioid metabolite, isolated.

Aliases (4)

7-hydroxymitragynine · 7-OH · 7-hydroxy-mitragynine · isolated 7-OH

TYPICAL DOSE

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ROUTE

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CYCLE

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STORAGE

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Overview

What is 7-OH-Mitragynine?

Kratom's high-affinity opioid metabolite, isolated. Functionally equivalent to mid-potency synthetic opioids. Multiple US deaths from commercial 7-OH products. SKIP-PERMANENT.

What to Expect

Week 1
Tolerability and dose-response.
Week 2-4
Early effect window.
Week 4-8
Peak benefit assessment.
Week 8+
Cycle decision point.

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Related compounds

Cross-referenced from 7-OH-Mitragynine

Primary indole alkaloid of Mitragyna speciosa (kratom). Comprises ~60-66% of total alkaloid content in dried leaf. Functionally a partial μ-opioid agonist + α2-adrenergic agonist + 5-HT2A partial agonist.

O-Desmethyltramadol

Active opioid metabolite of tramadol. Generated by CYP2D6 hepatic O-demethylation. ~200× higher μ-opioid receptor affinity than parent tramadol. Sold as research chemical in isolated form for euphoric / analgesic effects.